منابع مشابه
Antagonism of ketamine by 4-aminopyridine and physostigmine.
Saemund and Dalcnius reported five cases of nodal rhythm directly related to the injection of pancuronium 0.1 mgkg" •. We, too, have witnessed several examples of transient nodal rhythm after the administration of pancuronium and not infrequently this rhythm disturbance has been accompanied by a decrease in arterial pressure. Recent reviews (PrysRoberts, 1981) emphasize the potential deleteriou...
متن کاملAntagonism of neuromuscular block by physostigmine in man.
In 20 adult patients undergoing inguinal herniorrhaphy neuromuscular block was induced with tubocurarine 10 mg. In 10 patients, neostigmine 1--2 mg antagonized the block and restored the twitch response to its baseline value. Physostigmine, up to 4 mg, did not produce significant antagonism of the neuromuscular block.
متن کاملAntagonism of sevoflurane anaesthesia by physostigmine: effects on the auditory steady-state response and bispectral index.
BACKGROUND Physostigmine, a centrally acting anticholinesterase, antagonizes the hypnotic effect of propofol, as shown by the return of consciousness (response to commands) or wakefulness (spontaneous eye-opening without response to commands) and by recovery of auditory evoked potentials (40 Hz auditory steady-state response (ASSR)) and the bispectral index (BIS). We measured the effects of phy...
متن کاملAntagonism of ketamine-diazepam anaesthesia by 4-aminopyridine in human volunteers.
Five healthy human volunteers were anaesthetized on two separate occasions, 1 week apart, using a standard diazepam-ketamine induction followed by an infusion of ketamine for 1 h. Ten minutes after stopping the infusion, either 4-aminopyridine 0.3 mg kg--1 in saline or the same volume of saline alone was administered i.v. It was concluded that 4-aminopyridine enhanced dramatically the rate of r...
متن کاملBradycardia produced by pyridostigmine and physostigmine.
PURPOSE The bradycardia produced by pyridostigmine and physostigmine in an animal model of acute cardiac denervation was examined according to its relation to cholinesterase inhibition and sensitivity to block by cholinergic receptor antagonists. METHODS Cats were anaesthetised, vagotomised and propranolol-treated. Heart rate was continuously recorded. Erythrocyte cholinesterase activity of a...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1978
ISSN: 0007-0912
DOI: 10.1093/bja/50.1.81-a